Osadchiĭ L I, Balueva T V, Sergeev I V
Fiziol Zh Im I M Sechenova. 1996 Aug-Sep;82(8-9):43-53.
A significant decrease of systolic and diastolic effects occurred when initial level of the blood pressure had been elevated from 60 to 200 mm Hg with mesathone and from 70 to 185 mm Hg with polyglukine in anaesthesized rats. A reverse linear correlation was found between the above parameters at a high degree of connection for both agents. "Vascular" and "cardiac" mechanisms of revealed relationships are discussed.
在麻醉大鼠中,当血压初始水平从60毫米汞柱升高到200毫米汞柱使用美沙酮时,以及从70毫米汞柱升高到185毫米汞柱使用聚明胶肽时,收缩压和舒张压效应均显著降低。在两种药物高度相关的情况下,发现上述参数之间呈反向线性关系。文中讨论了所揭示关系的“血管”和“心脏”机制。