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[围生期诱导的缺氧缺血性脑病?从神经儿科角度进行回顾性评估的可能性]

[Perinatally-induced hypoxic-ischemic encephalopathy? Possibilities of retrospective evaluation from the neuropediatric viewpoint].

作者信息

Niemann G, Vollmer B, Goelz R

机构信息

Universitäts-Kinderklinik, Abteilung für Entwicklungsneurologie and Neuropädiatrie, Tübingen.

出版信息

Z Geburtshilfe Neonatol. 1996 Sep-Oct;200(5):202-5.

PMID:9035831
Abstract

This paper analyzes the feasibility of determining retrospectively, from a neuropediatric standpoint, whether an existing neurological disorder can be traced back to a perinatal hypoxic-ischemic encephalopathy. In principal, we can assume that there is a correlation between this time and pathogenesis of the brain injury on the one hand and the neurological symptoms on the other if these conditions are fulfilled 1. In the first days of live term infants revealed cerebral symptoms (like abnormality of muscle tone and consciousness and seizures) which manifest themselves in a typical sequence and are combined with involvement of other organ systems. In pre-term infants the clinical signs are often not clearly definable. 2. The subsequent neurological disorder after the primary symptoms must be a spastic-less commonly in term infants a dyskinetic one. 3. Lesions typical for the child's gestational age are visible on magnetic resonance imaging.

摘要

本文从神经儿科学的角度分析了对现有神经系统疾病能否追溯至围生期缺氧缺血性脑病进行回顾性判定的可行性。原则上,如果满足以下条件,我们可以假定一方面这段时间与脑损伤的发病机制之间,另一方面与神经症状之间存在关联:1. 足月新生儿在出生后的头几天出现脑部症状(如肌张力和意识异常以及惊厥),这些症状按典型顺序出现,并伴有其他器官系统受累。早产儿的临床体征往往难以明确界定。2. 原发性症状出现后的后续神经系统疾病必须是痉挛型的——足月儿较少见的是运动障碍型。3. 在磁共振成像上可见与患儿胎龄相符的典型病变。

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