Mittelmeier W, Braun C, Gradinger R
Klinik für Orthopädie, Medizinischen Universität zu Lübeck.
Chirurg. 1996 Nov;67(11):1087-92. doi: 10.1007/s001040050108.
Different bone substitutes exist for reconstruction of segmental tibial bone defects. The choice of bone substitute is limited by the quality of the surrounding tissue and the size of the bone defect. Especially in large bone defects, the freely or microvascularly transferred autogenic graft should be preferred. Allogenic transplants or artificial bone substitutes, such as spongy calcium phosphate materials, are suitable only for implantation in smaller, well-vascularized bone defects or as an additional procedure in large bone defects. In infected cases, allogenic and artificial, especially slowly resorbable implants, have to be avoided. The prerequisite for defect reconstruction is stable internal fixation.
存在多种不同的骨替代物用于重建胫骨节段性骨缺损。骨替代物的选择受到周围组织质量和骨缺损大小的限制。特别是在大的骨缺损中,应优先选择游离或带微血管蒂的自体移植骨。同种异体移植或人工骨替代物,如海绵状磷酸钙材料,仅适用于植入较小的、血运良好的骨缺损或作为大骨缺损的辅助手术。在感染病例中,必须避免使用同种异体和人工的,尤其是吸收缓慢的植入物。缺损重建的前提是稳定的内固定。