Ulmer A, Dietl J, Schaumburg-Lever G, Fierlbeck G
Universitäts-Hautklinik, Tübingen.
Hautarzt. 1996 Nov;47(11):854-7. doi: 10.1007/s001050050520.
Malignant melanoma of the vulva is an uncommon disease. The amelanotic subtype is only rarely mentioned. We report a 60-year-old patient with a 6 month history of vulvar pruritus. Ivory lesions combined with erosions and fine "cigarette paper'-like wrinkling were suspicious for lichen sclerosus et atrophicus. Histologically the diagnosis of an amelanotic malignant melanoma was made. Amelanotic melanoma may present with a wide variety of clinical features. Even in the uncommon location of the vulva, amelanotic melanoma should be suspected in any nonhealing nonpigmented lesion.
外阴恶性黑色素瘤是一种罕见疾病。无色素亚型很少被提及。我们报告一名60岁患者，有6个月的外阴瘙痒病史。象牙色病变伴有糜烂和细微的“卷烟纸”样皱纹，怀疑为硬化性苔藓萎缩型。组织学诊断为无色素性恶性黑色素瘤。无色素性黑色素瘤可能呈现出各种各样的临床特征。即使在外阴这个不常见的部位，任何不愈合的无色素病变都应怀疑有无色素性黑色素瘤。
