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肢体缺血:急性动脉闭塞的外科治疗

Limb ischemia: surgical therapy in acute arterial occlusion.

作者信息

Neuzil D F, Edwards W H, Mulherin J L, Martin R S, Bonau R, Eskind S J, Naslund T C, Edwards W H

机构信息

Division of Vascular Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37212-3735, USA.

出版信息

Am Surg. 1997 Mar;63(3):270-4.

PMID:9036898
Abstract

Mortality and amputation rates from acute arterial occlusion are reported from 7 to 37 per cent and 10 to 30 per cent, respectively. Recent data from thrombolysis or peripheral arterial surgery suggest no significant differences between initial management with surgical or thrombolytic therapy. Mortality and amputation rates were in the above ranges. The last 230 procedures (216 patients) over 10 years were reviewed. All graft occlusions, cardiac catheterization injuries, and aortic balloon-related thromboses were excluded. Immediate and delayed amputation rates were 6.5 and 0.9 per cent. Death occurred in 21 patients (9.7%), with only 6 deaths over the last 6 years (3.8%). Except for transesophageal echocardiography, perioperative studies were of limited value. Long-term anticoagulation was also not effective in preventing recurrent episodes. A mortality rate of 9.7 per cent and amputation rate of 7.4 per cent justifies an early aggressive surgical approach. Limited perioperative studies and less prolonged anticoagulation may also improve cost containment.

摘要

急性动脉闭塞的死亡率和截肢率分别报道为7%至37%和10%至30%。近期来自溶栓或外周动脉手术的数据表明,手术治疗或溶栓治疗的初始处理之间无显著差异。死亡率和截肢率处于上述范围。回顾了过去10年中的最后230例手术(216例患者)。所有移植血管闭塞、心导管插入术损伤和主动脉球囊相关血栓形成均被排除。即刻和延迟截肢率分别为6.5%和0.9%。21例患者死亡(9.7%),过去6年仅有6例死亡(3.8%)。除经食管超声心动图外,围手术期研究价值有限。长期抗凝在预防复发方面也无效。9.7%的死亡率和7.4%的截肢率证明应采取早期积极的手术方法。有限的围手术期研究和较短时间的抗凝也可能有助于控制成本。

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