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电射精法在治疗糖尿病继发射精功能障碍中的应用。

Use of electroejaculation in the treatment of ejaculatory failure secondary to diabetes mellitus.

作者信息

Gerig N E, Meacham R B, Ohl D A

机构信息

Department of Surgery, University of Colorado Health Sciences Center, Denver 80262, USA.

出版信息

Urology. 1997 Feb;49(2):239-42. doi: 10.1016/S0090-4295(96)00444-X.

Abstract

OBJECTIVES

To describe the experience of two male fertility programs using electroejaculation (EEJ) in the management of men with ejaculatory failure secondary to diabetes mellitus.

METHODS

Twenty-nine EEJ procedures were performed in 7 diabetic men with ejaculatory failure. Results were reviewed with attention paid to sperm characteristics in both antegrade and retrograde specimens as well as pregnancy rates.

RESULTS

Retrograde semen specimens retrieved from the bladder following EEJ contained a mean of 3444.5 million sperm (range 269.2 to 4996 million). Antegrade specimens contained a mean of 698.8 million sperm (range 226.8 to 1961 million). Mean sperm motility was 4% for retrograde specimens (range 0% to 11%) and 7% for antegrade specimens (1% to 15%). In all but 1 case, semen specimens were used for intrauterine insemination. The total number of motile sperm contained in the processed, inseminated specimens ranged from 1 to 87.2 million. In 1 case, the sperm obtained through EEJ was used in an in vitro fertilization procedure.

CONCLUSIONS

EEJ can be successfully used to obtain sperm from men with ejaculatory failure due to diabetes mellitus. The procedure requires general anesthesia, and pregnancy rates after intrauterine insemination with the processed sperm are low. Advanced reproductive technologies may offer a feasible alternative, providing higher success rates with fewer procedures.

摘要

目的

描述两个男性生育项目使用电射精(EEJ)管理因糖尿病继发射精功能障碍男性的经验。

方法

对7例射精功能障碍的糖尿病男性患者进行了29次电射精操作。回顾结果时关注顺行和逆行标本中的精子特征以及妊娠率。

结果

电射精后从膀胱中获取的逆行精液标本平均含有34.445亿个精子(范围为2.692亿至49.96亿)。顺行标本平均含有6.988亿个精子(范围为2.268亿至19.61亿)。逆行标本的平均精子活力为4%(范围为0%至11%),顺行标本为7%(1%至15%)。除1例患者外,所有精液标本均用于宫内人工授精。处理后用于授精的标本中活动精子总数为100万至八千七百万。有1例患者,通过电射精获得的精子用于体外受精程序。

结论

电射精可成功用于从因糖尿病导致射精功能障碍的男性中获取精子。该操作需要全身麻醉,使用处理后的精子进行宫内人工授精后的妊娠率较低。先进的生殖技术可能提供一种可行的替代方法,成功率更高且操作次数更少。

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