Catalano G, Catalano M C, Taylor W
Department of Psychiatry and Behavioral Medicine, University of South Florida College of Medicine, Tampa, USA.
Clin Neuropharmacol. 1997 Feb;20(1):82-5. doi: 10.1097/00002826-199702000-00010.
Risperidone (Risperdal) is a recently released novel antipsychotic medication. It is different from the conventional neuroleptics, such as haloperidol, as it has both serotinergic and dopaminergic activity. It has a more tolerable side-effect profile compared with other antipsychotic medications. We review the literature regarding the side effects of risperidone use, describe a case of overdose with risperidone, and discuss the clinical sequelae and management of such an overdose.
利培酮(维思通)是一种最近上市的新型抗精神病药物。它与传统的抗精神病药物如氟哌啶醇不同,因为它同时具有5-羟色胺能和多巴胺能活性。与其他抗精神病药物相比,它的副作用更容易耐受。我们回顾了关于使用利培酮副作用的文献,描述了一例利培酮过量的病例,并讨论了这种过量用药的临床后果及处理方法。