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假性热变形红细胞症:一种显著的人为现象。

Pseudopyropoikilocytosis: a striking artefact.

作者信息

Bain B J, Liesner R

机构信息

Department of Haematology, St Mary's Hospital Medical School, London.

出版信息

J Clin Pathol. 1996 Sep;49(9):772-3. doi: 10.1136/jcp.49.9.772.

DOI:10.1136/jcp.49.9.772
PMID:9038768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC500733/
Abstract

The blood films both of patients with hereditary pyropoikilocytosis and of those with severe thermal burns are characterised by budding erythrocytes and the presence of microspherocytes. Recently, a fourth example of similar morphological features, caused by overheating of a blood specimen in a motor vehicle during transport to the laboratory, has been observed. It is important to be aware of this artefact as failure to recognise it is likely to lead to diagnostic confusion and unnecessary further testing, causing inconvenience to the patient.

摘要

遗传性热异形红细胞增多症患者和严重热烧伤患者的血涂片均以出芽红细胞和小球形红细胞的存在为特征。最近,在将血标本运送到实验室的过程中,因机动车内血标本过热而出现类似形态特征的第四个病例已被观察到。认识到这种人为现象很重要,因为未能识别它可能会导致诊断混乱和不必要的进一步检查,给患者带来不便。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6b/500733/ab572fe9cbc2/jclinpath00246-0079-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6b/500733/e28b38f06555/jclinpath00246-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6b/500733/ab572fe9cbc2/jclinpath00246-0079-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6b/500733/e28b38f06555/jclinpath00246-0079-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6b/500733/ab572fe9cbc2/jclinpath00246-0079-b.jpg

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Pseudopyropoikilocytosis: a striking artefact.假性热变形红细胞症:一种显著的人为现象。
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引用本文的文献

1
Pseudopyropoikilocytosis leading to spurious results.假性热变性异形红细胞症导致结果出现偏差。
Sultan Qaboos Univ Med J. 2014 May;14(2):e259-60. Epub 2014 Apr 7.

本文引用的文献

1
Focal rhabdomyosarcomatous differentiation in primary liposarcoma.原发性脂肪肉瘤中的局灶性横纹肌肉瘤样分化。
J Clin Pathol. 1996 Sep;49(9):770-2. doi: 10.1136/jcp.49.9.770.
2
A congenital haemolytic anaemia with thermal sensitivity of the erythrocyte membrane.一种红细胞膜具有热敏感性的先天性溶血性贫血。
Br J Haematol. 1975 Apr;29(4):537-43. doi: 10.1111/j.1365-2141.1975.tb02740.x.