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原发性脂肪肉瘤中的局灶性横纹肌肉瘤样分化。

Focal rhabdomyosarcomatous differentiation in primary liposarcoma.

作者信息

Shanks J H, Banerjee S S, Eyden B P

机构信息

Department of Histopathology, Christie Hospital NHS Trust, Withington, Manchester.

出版信息

J Clin Pathol. 1996 Sep;49(9):770-2. doi: 10.1136/jcp.49.9.770.

DOI:10.1136/jcp.49.9.770
PMID:9038767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC500732/
Abstract

A unique case of primary myxoid liposarcoma of the thigh, in which focal pleomorphic areas were present containing rhabdomyoblasts, is described. Focal rhabdomyosarcoma in liposarcoma has only rarely been reported previously and only in dedifferentiated liposarcomas of the retroperitoneum. All but one have been recurrences with rhabdomyoblasts being absent in the primary liposarcoma. As rhabdomyoblasts were only focally present, the present case is regarded as liposarcoma with focal divergent rhabdomyoblastic differentiation rather than malignant mesenchymoma.

摘要

本文描述了一例罕见的大腿原发性黏液样脂肪肉瘤,其中存在含有横纹肌母细胞的局灶性多形性区域。脂肪肉瘤中局灶性横纹肌肉瘤此前仅有极少报道,且仅见于腹膜后去分化脂肪肉瘤。除1例之外,其余均为复发病例,原发性脂肪肉瘤中不存在横纹肌母细胞。由于横纹肌母细胞仅局灶性存在,故本病例被视为具有局灶性异向横纹肌母细胞分化的脂肪肉瘤,而非恶性间叶瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7535/500732/b1926e615eba/jclinpath00246-0077-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7535/500732/d338c41997da/jclinpath00246-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7535/500732/b1926e615eba/jclinpath00246-0077-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7535/500732/d338c41997da/jclinpath00246-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7535/500732/b1926e615eba/jclinpath00246-0077-b.jpg

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本文引用的文献

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Ann Surg. 1948 Feb;127(2):278-90. doi: 10.1097/00000658-194802000-00007.
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Divergent myosarcomatous differentiation in retroperitoneal liposarcoma.腹膜后脂肪肉瘤中的异向性肌肉瘤分化
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Dedifferentiated liposarcoma. Clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas.去分化脂肪肉瘤。32例临床病理分析提示多形性肉瘤中存在预后较好的亚组。
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Myxoid liposarcoma with cartilaginous differentiation: a case study with cytogenetical analysis.伴有软骨分化的黏液样脂肪肉瘤:一项细胞遗传学分析的病例研究
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Pseudopyropoikilocytosis: a striking artefact.假性热变形红细胞症:一种显著的人为现象。
J Clin Pathol. 1996 Sep;49(9):772-3. doi: 10.1136/jcp.49.9.772.
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Divergent differentiation in soft tissue sarcomas.软组织肉瘤中的分化差异
J Clin Pathol. 1996 Sep;49(9):697-8. doi: 10.1136/jcp.49.9.697.
Am J Surg Pathol. 1994 Dec;18(12):1213-23. doi: 10.1097/00000478-199412000-00004.
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Heterologous elements in the dedifferentiated component of dedifferentiated liposarcoma.去分化脂肪肉瘤去分化成分中的异源成分。
Am J Surg Pathol. 1994 Nov;18(11):1150-7. doi: 10.1097/00000478-199411000-00009.
5
Soft-tissue sarcomas of adults; study of pathological prognostic variables and definition of a histopathological grading system.成人软组织肉瘤;病理预后变量研究及组织病理学分级系统的定义
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Dedifferentiated liposarcoma with features of rhabdomyosarcoma.具有横纹肌肉瘤特征的去分化脂肪肉瘤。
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