原发性卵巢癌异位分泌促肾上腺皮质激素导致的库欣综合征。

Cushing's syndrome secondary to ectopic ACTH secretion from a primary ovarian carcinoma.

作者信息

Ball S G, Davison J M, Burt A D, McNicol A M, Baylis P H

机构信息

Department of Obstetrics and Gynaecology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

出版信息

Clin Endocrinol (Oxf). 1996 Dec;45(6):775-8. doi: 10.1046/j.1365-2265.1996.8670877.x.

DOI:10.1046/j.1365-2265.1996.8670877.x

PMID:9039345

Abstract

We report a 63-year-old woman who presented with clinical and biochemical features of ACTH dependent Cushing's syndrome secondary to a primary ovarian carcinoma. The tumour produced very high levels of ACTH precursors, consistent with defective POMC processing.

摘要

我们报告了一名63岁女性，其表现出继发于原发性卵巢癌的促肾上腺皮质激素（ACTH）依赖性库欣综合征的临床和生化特征。该肿瘤产生了非常高水平的ACTH前体，这与阿黑皮素原（POMC）加工缺陷一致。