Lewis I J
Department of Paediatric Oncology and Haematology, St James's University Hospital, Leeds, UK.
Br Med Bull. 1996 Oct;52(4):887-97. doi: 10.1093/oxfordjournals.bmb.a011589.
Adolescence is a flexible concept reflecting specific developmental tasks but broadly encompassing individuals in their teens and early twenties. Comparison of published data from cancer registries demonstrates that the incidence of cancer (rate/10(6)/year) increases through the 5 year age bands 10-14 (range 100-130.1 for males, 80-115.3 for females), 15-19 (range 154.3-220.7 for males, 127-206.7 for females) and 20-24 (229 for males, 313 for females). Leukaemia and central nervous system tumours predominate in the 10-14 year group but during mid and late adolescence lymphomas become the main single tumour group and epithelial cancers become increasingly common. Arguments are presented for the formation of specialised adolescent cancer units based on the premise that centralisation of care would lead to improved treatment and survival. The physical, psychological, social and educational needs of adolescents are best served by the expertise of a single multidisciplinary team.
青春期是一个灵活的概念,反映了特定的发育任务,但广泛涵盖十几岁和二十出头的个体。对癌症登记处公布数据的比较表明,癌症发病率(每10^6人/年)在10 - 14岁(男性范围为100 - 130.1,女性为80 - 115.3)、15 - 19岁(男性范围为154.3 - 220.7,女性为127 - 206.7)和20 - 24岁(男性为229,女性为313)这三个5岁年龄组中呈上升趋势。白血病和中枢神经系统肿瘤在10 - 14岁组中占主导地位,但在青春期中期和后期,淋巴瘤成为主要的单一肿瘤组,上皮癌也越来越常见。基于集中护理将改善治疗和生存率这一前提,有人主张设立专门的青少年癌症治疗单位。青少年的身体、心理、社会和教育需求最好由单一的多学科团队的专业知识来满足。