Bond M G, Workman G, Martland J, Clinkard J E, Carey B M, Rothwell R I, Joslin C A, Heron D A
Cookridge Hospital, Leeds, UK.
Clin Oncol (R Coll Radiol). 1997;9(1):41-7. doi: 10.1016/s0936-6555(97)80060-x.
A series of 23 patients with early adenocarcinoma of the endometrium who underwent a total of 37 modified Heyman packings treated on a high dose rate Microselectron has been reviewed. Using computed tomography (CT), the uterine wall thickness was measured retrospectively and doses calculated at a number of points on the uterine serosa and related normal tissues. The mean and maximum fundal serosal doses were found to be highest posteriorly and the sigmoid colon was adjacent to the posterior surface of the uterus in all instances. By superimposing the isodose distribution on CT sections of the uterus, it is now possible to prescribe to a serosal dose, or, in patients too heavy for the CT scanner, a dose can be prescribed to a point S, which is a reasonable approximation to the serosal position. Since the initial study, a further ten patients have been treated by the same method and, where relevant, data from all 33 patients have been used.
回顾了一组23例子宫内膜早期腺癌患者，这些患者在高剂量率微型后装治疗机上共接受了37次改良海曼填塞治疗。利用计算机断层扫描（CT），对子宫壁厚度进行了回顾性测量，并计算了子宫浆膜和相关正常组织上多个点的剂量。发现子宫底部浆膜的平均剂量和最大剂量在后部最高，并且在所有情况下乙状结肠都与子宫后表面相邻。通过将等剂量分布叠加在子宫的CT切片上，现在可以规定浆膜剂量，或者，对于体重过重无法使用CT扫描仪的患者，可以规定到点S的剂量，点S是浆膜位置的合理近似值。自最初的研究以来，又有10例患者采用相同方法进行了治疗，并且在相关情况下，使用了所有33例患者的数据。
