Ito T, Kadowaki K, Takahashi H, Nagata N, Makio A, Terakawa N
Department of Obstetrics and Gynecology, Tottori University School of Medicine, Yonago, Japan.
Early Hum Dev. 1997 Jan 20;47(2):195-201. doi: 10.1016/s0378-3782(96)01779-3.
To clarify the clinical features of and cardiotocographic findings for premature infants with antenatal periventricular leukomalacia (PVL).
Antenatal PVL was judged to be present if a cyst greater than 3 mm in largest diameter was detected in the periventricular region by the 14th day of life on cranial ultrasonography. The clinical features of and cardiotocographic findings for 12 premature infants with antenatal PVL born within 1 year were compared with those of 12 infants chosen as control group matched in gestational age at birth from the premature infants without antenatal PVL born within the study period.
Abnormalities of the umbilical cord such as coiling, excessive torsion and membrane insertion were observed more frequently for infants with antenatal PVL (58.3%) than for control infants (16.7%) (P<0.05). Frequent moderate variable deceleration on the fetal cardiogram was also observed more frequently for infants with antenatal PVL (80.0%) than for control infants (27.3%) (P<0.05).
Abnormalities of the umbilical cord and frequent moderate variable deceleration on fetal cardiotocogram appear to be causes of antenatal PVL in premature infants.
阐明产前脑室周围白质软化（PVL）早产儿的临床特征及胎心监护结果。
若在出生后14天内头颅超声检查发现脑室周围区域存在最大直径大于3mm的囊肿，则判定存在产前PVL。将1年内出生的12例产前PVL早产儿的临床特征及胎心监护结果，与研究期间出生的无产前PVL早产儿中按出生孕周匹配的12例婴儿作为对照组进行比较。
产前PVL婴儿（58.3%）脐带异常如缠绕、过度扭转及胎膜附着等情况比对照组婴儿（16.7%）更常见（P<0.05）。产前PVL婴儿（80.0%）胎心监护中频繁出现中度变异减速的情况也比对照组婴儿（27.3%）更常见（P<0.05）。
脐带异常及胎心监护中频繁出现中度变异减速似乎是早产儿产前PVL的病因。
