Yedidag A, Zikos D, Spargo B, MacEntee P, Berkelhammer C
Department of Gastroenterology, Christ Hospital & Medical Center, Oak Lawn, Illinois 60453, USA.
Am J Gastroenterol. 1997 Feb;92(2):326-8.
Malignancy is a cause of membranous glomerulonephritis. We report a patient with an otherwise asymptomatic squamous cell carcinoma of the esophagus whose presenting manifestation was membranous glomerulonephritis and nephrotic syndrome. Perinuclear anti-neutrophil cytoplasmic antibody was positive. This is the first reported case of perinuclear anti-neutrophil cytoplasmic antibody associated with paraneoplastic glomerulonephritis and nephrotic syndrome due to esophageal squamous cell carcinoma.
恶性肿瘤是膜性肾小球肾炎的一个病因。我们报告一例患者，其患有食管鳞状细胞癌，在其他方面无症状，但其首发表现为膜性肾小球肾炎和肾病综合征。核周型抗中性粒细胞胞浆抗体呈阳性。这是首例报道的因食管鳞状细胞癌导致的核周型抗中性粒细胞胞浆抗体与副肿瘤性肾小球肾炎及肾病综合征相关的病例。
