Sheppard M N, Hansell D M, Du Bois R M, Nicholson A G
Department of Histopathology, Royal Brompton Hospital, London, UK.
Hum Pathol. 1997 Mar;28(3):383-5. doi: 10.1016/s0046-8177(97)90140-4.
Pulmonary angiosarcomas are usually secondary tumors, and only a few primary cases have been described. We report a unique case of epithelioid angiosarcoma arising in the lungs as a bilateral multinodular infiltrate and presenting as pulmonary hemorrhage. Because of its epithelioid histology, this tumor may resemble a carcinoma, also staining positively for keratin markers. Therefore, unless the diagnosis of epithelioid angiosarcoma is considered and endothelial markers used, the diagnosis of epithelioid angiosarcoma may be overlooked at this site.
肺血管肉瘤通常是继发性肿瘤，仅有少数原发性病例被报道。我们报告了一例独特的上皮样血管肉瘤病例，该肿瘤发生于肺部，表现为双侧多结节浸润并伴有肺出血。由于其上皮样组织学特征，该肿瘤可能类似于癌，对角蛋白标志物也呈阳性染色。因此，除非考虑上皮样血管肉瘤的诊断并使用内皮标志物，否则该部位的上皮样血管肉瘤诊断可能会被忽视。
