Bell W H, Harper R P, Gonzalez M, Cherkashin A M, Samchukov M L
Department of Oral Maxillofacial Surgery, Baylor College of Dentistry, Dallas, Texas 75266-0677, USA.
Br J Oral Maxillofac Surg. 1997 Feb;35(1):11-9. doi: 10.1016/s0266-4356(97)90003-6.
The purpose of this investigation was to elucidate the biology of distraction osteogenesis during mandibular widening. Midsymphyseal vertical interdental osteotomies were performed in nine Macaca mulatta monkeys. After a latency period a tooth-borne appliance was activated at a rate of 0.5 mm twice a day for 7-10 days. The appliance was then stabilized for a period of 4 or 8 weeks. The distraction gap at the inferior portion of the symphysis was bridged completely by new bony trabeculae. Bone formation in the interdental area was apparently related to the surgical technique. Newly formed bony trabeculae were oriented parallel to the direction of distraction. The location of the osteotomy site with an adequate margin of alveolar bone contiguous with the adjacent teeth was necessary for the induction of the distraction osteogenesis. Disproportional movement between superior and inferior portions of the distracted segments was noted.
本研究的目的是阐明下颌骨扩宽过程中牵张成骨的生物学特性。对9只恒河猴进行了正中联合部垂直牙间截骨术。经过一段潜伏期后，每天以0.5毫米的速度激活牙支持式矫治器两次，持续7 - 10天。然后将矫治器固定4周或8周。联合部下方的牵张间隙被新的骨小梁完全桥接。牙间区域的骨形成显然与手术技术有关。新形成的骨小梁与牵张方向平行排列。截骨部位位于与相邻牙齿相邻的牙槽骨有足够边缘处，这对诱导牵张成骨是必要的。注意到牵张节段的上部和下部之间存在不成比例的移动。
