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[声门型喉癌分期中的放射治疗。I. 结果及预后因素分析]

[Radiation therapy in glottic laryngeal carcinoma stage. I. Results and analysis of prognostic factors].

作者信息

Skołyszewski J, Reinfuss M, Kowalska T, Walasek T, Dymek P

机构信息

Kliniki Radioterapii Centrum Onkologii Instytutu im. M. Skłodowskiej-Curie w Krakowie.

出版信息

Otolaryngol Pol. 1996;50(3):243-7.

PMID:9045160
Abstract

Two hundred and forty-five patients with stage I glottic laryngeal cancer were treated with radiotherapy in Center of Oncology in Kraków between 1973 and 1988. One hundred and fifty-five patients were irradiated with Co-60 unit, 90 patients with mixed photon-electron beam. The 5-year NED survival rates after the radiotherapy only were 85.3%, after the radiotherapy and surgery for recurrences--95.1%. The sex, age, local extension of primary tumor (T1a vs. T1b), location of the tumor on true vocal cord and involvement of anterior commissure were evaluated in a uni- and multivariate analysis of prognostic factors. For the end-point of 5-year NED survival no statistically significant relationship was found between results and analysis variables.

摘要

1973年至1988年间,克拉科夫肿瘤中心对245例I期声门型喉癌患者进行了放射治疗。155例患者接受了钴-60单位照射,90例患者接受了混合光子-电子束照射。单纯放疗后的5年无病生存率为85.3%,放疗及复发后手术的5年无病生存率为95.1%。在对预后因素的单因素和多因素分析中,评估了患者的性别、年龄、原发肿瘤的局部扩展(T1a与T1b)、肿瘤在真声带的位置以及前联合受累情况。对于5年无病生存这一终点,未发现结果与分析变量之间存在统计学上的显著关系。

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