Scutellari P N, Orzincolo C, Bedani P L, Romano C
Istituto di Radiologia, Università degli Studi di Ferrara.
Radiol Med. 1996 Oct;92(4):415-20.
Forty-five patients affected with chronic renal failure (29 men and 16 women; mean age: 47.8 years), treated with hemodialysis for 4 to 245 months (mean: 66.9 months) were examined with panoramic and skeletal radiographs-the latter of the skull, hands, shoulders and clavicles, pelvis and spine. The control group (45 subjects with no renal diseases) was examined only with panoramic radiography. Dental and skeletal radio-graphs were given an 0-6 score and then compared to assess a possible relationship between skeletal and dental changes at radiography. Twenty-six dialysis patients (57.7%) had radiographic abnormalities in the maxillary bones-i.e., osteoporosis (100% of patients), focal osteosclerosis adjacent to the roots (11.5%), lamina dura reduction or loss (26.9%), calcifications of soft tissues or salivary glands (15.3%) and brown tumors (7.6%). In the teeth of dialysis patients, the dental pulp chamber was narrowed in 11.1% and hypercementosis of the roots was observed in 4.5%. Radiographic abnormalities in the hand, shoulder and pelvis were depicted in 51.1% of dialysis patients-in 86.9% of them with maxillary lesions. In the control group, 15.5% had mandibular bone lesions-i.e., osteopenia, cortex reduction at the mandibular angles and cyst-like lesions -but the evidence of caries and periodontal disease did not differ from that in the dialysis group. The diagnosis and follow-up of dialysis patients are currently made with serum biochemistry, radiography and histology. The purpose of skeletal radiology is to monitor the progression or regression of musculoskeletal abnormalities. Panoramic radiography might be useful in monitoring renal osteodystrophy, especially to assess the response to therapy-i.e., parathyroidectomy, calcium or vitamin-D therapy and renal transplant.
45例慢性肾衰竭患者(29例男性,16例女性;平均年龄:47.8岁),接受血液透析治疗4至245个月(平均:66.9个月),接受了全景和骨骼X线检查——后者包括颅骨、手部、肩部和锁骨、骨盆及脊柱。对照组(45例无肾脏疾病的受试者)仅接受全景X线检查。对牙齿和骨骼X线片进行0至6分评分,然后进行比较,以评估X线检查时骨骼和牙齿变化之间可能存在的关系。26例透析患者(57.7%)上颌骨存在X线异常——即骨质疏松(100%的患者)、牙根周围局灶性骨硬化(11.5%)、硬骨板变薄或缺失(26.9%)、软组织或唾液腺钙化(15.3%)以及棕色瘤(7.6%)。在透析患者的牙齿中,11.1%的患者牙髓腔变窄,4.5%的患者观察到牙根骨质增生。51.1%的透析患者手部、肩部和骨盆存在X线异常——其中86.9%伴有上颌病变。对照组中,15.5%的患者存在下颌骨病变——即骨质减少、下颌角皮质变薄和囊肿样病变——但龋齿和牙周疾病的情况与透析组无差异。目前,透析患者的诊断和随访通过血清生化检查、X线检查和组织学检查进行。骨骼放射学的目的是监测肌肉骨骼异常的进展或消退。全景X线检查可能有助于监测肾性骨营养不良,特别是评估对治疗的反应——即甲状旁腺切除术、钙或维生素D治疗以及肾移植。