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[使用抗氧化剂治疗流感相关性肺炎]

[The treatment of pneumonias in influenza using antioxidants].

作者信息

Nagibina M V, Neĭfakh E A, Krylov V F, Braginskiĭ D M, Kulagina M G

出版信息

Ter Arkh. 1996;68(11):33-5.

PMID:9045374
Abstract

Lipid peroxidation (LPO) has been studied in patients with influenza complicated by pneumonia as shown by GPL and MDA serum levels of GPL and MDA. Acute period of the disease was characterized by a sharp rise in LPO products production, especially in seriously ill patients. Administration of alpha-tocopherol promoted a significant decrease of MDA and GPL levels and more apparent clinical response. Dibunol caused minimal changes in the disease clinical pictures and LPO activity.

摘要

脂质过氧化(LPO)已在流感并发肺炎患者中进行了研究,通过血清中脂质过氧化物(GPL)和丙二醛(MDA)水平得以体现。疾病急性期的特征是LPO产物生成急剧增加,尤其是在重症患者中。给予α-生育酚可促使MDA和GPL水平显著降低,并带来更明显的临床反应。二丁基羟基甲苯(Dibunol)对疾病临床表现和LPO活性的影响极小。

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