[The anti-ulcer action of dibunol (Tonarol)].
作者信息
Zarudiĭ R F, Myshkin V A, Zarudiĭ F S, Ismagilova A F, Davydova V A
机构信息
Bashkir State Medical University, Institute of Organic Chemistry, Russian Academy of Sciences, Ufa, Russia.
出版信息
Eksp Klin Farmakol. 1998 Sep-Oct;61(5):21-3.
PMID:9854627
Abstract
In experimental study of antiulcerative activity of dibunol on various models of gastric ulcers in rats the drug caused a marked antiulcerative effect in all of them, reduced the incidence of ulcer formation, and shortened the time of ulcer healing. In a model of "acetic" ulcer dibunol oil solution led to quick normalization of lipid peroxidation in the gastric mucosa, which was evidence of high antioxidant activity in cases of ulcer lesions.
摘要
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