Kadyrov S N, Tsinzerling V A, Amineva Kh K, Komarova D V
Ter Arkh. 1996;68(11):7-11.
Postmortem morphological examination of 102 cases with diphtheria who had died on the disease day 1-120 was performed. All the dead patients were adults. Dystrophic-necrotic processes in cardiac conduction and intramural nervous systems, in contractile myocardium developing on the disease day 1-8 were found. The severity and extent of these processes depended on toxic and hypoxic factors resultant from obturation or ventilation respiratory failure. Myocarditis progression undergoes 2 stages: early, exudative (beginning on the disease day 3) and late, productive (beginning on the disease day 9). The disease eventuated in myocardiosclerosis starting after 28-day course. Morphologically, diphtheritic cardiac lesion differed from cardiac damage caused by other acute infections.
对102例于发病第1至120天死亡的白喉患者进行了尸体解剖形态学检查。所有死亡患者均为成年人。发现在发病第1至8天，心脏传导系统和壁内神经系统以及收缩性心肌出现营养不良性坏死过程。这些过程的严重程度和范围取决于阻塞性或通气性呼吸衰竭导致的毒性和缺氧因素。心肌炎进展经历两个阶段：早期为渗出性（发病第3天开始），晚期为增生性（发病第9天开始）。病程28天后开始出现心肌硬化。形态学上，白喉性心脏病变与其他急性感染引起的心脏损伤不同。
