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[透析液的过滤与照射以预防血液透析期间的菌血症(作者译)]

[Filtration and irradiation of the dialysis fluid to prevent bacteriemia during hemodialysis (author's transl)].

作者信息

Tolon M, Botzenhart K, Wilbrandt R, Alsleben J

出版信息

Med Klin. 1977 Sep 9;72(36):1451-4.

PMID:904542
Abstract

For prevention of bacteriemia caused by contaminated dialysis fluid it is necessary to protect the dialysator by decontamination of the fluid immediately before entering the dialysator. Using filters with a pore size of 0.2 micrometer or 0.45 micrometer sterile samples of dialysis fluid could be obtained, but flow rate and pressure of the fluid could not be kept constant, when the resistance of the filter increased during use. With UV-lamps no problems concerning flow rate or pressure were encountered, but really satisfying results emerged only in laboratory experiments. This was due to causes which can be influenced by technical improvements of the irradiation unit, while the use of filters implies additional measures at the monitor unit to control flow rate and pressure. The success of the applied antimicrobial techniques should be monitored for not inducing a false conviction of safety.

摘要

为预防因透析液污染引起的菌血症,有必要在透析液进入透析器之前立即对其进行净化处理,以保护透析器。使用孔径为0.2微米或0.45微米的过滤器,可以获得无菌的透析液样本,但在使用过程中,当过滤器阻力增加时,液体的流速和压力无法保持恒定。使用紫外线灯时,未遇到流速或压力方面的问题,但只有在实验室实验中才出现了真正令人满意的结果。这是由于一些可以通过照射装置的技术改进来影响的原因,而使用过滤器则意味着在监测单元采取额外措施来控制流速和压力。应监测所应用的抗菌技术的成功情况,以免产生安全错觉。

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