Cowen P, O'Keefe R
Monash Medical Centre, Clayton, Victoria, Australia.
Australas J Dermatol. 1997 Feb;38(1):40-1. doi: 10.1111/j.1440-0960.1997.tb01099.x.
A 65-year-old man presented with a widespread erythematous maculopapular eruption. Skin biopsy showed spongiosis and focal acantholytic dyskeratosis consistent with Grover's disease. Clinically the eruption evolved to erythroderma with typical features of pityriasis rubra pilaris. On review of the histology, changes consistent with this diagnosis were also present in addition to the acantholytic dyskeratosis.
一名65岁男性出现广泛的红斑性斑丘疹。皮肤活检显示海绵形成和局灶性棘层松解性角化不良,符合格罗弗病。临床上,皮疹发展为红皮病,具有毛发红糠疹的典型特征。复查组织学检查时,除棘层松解性角化不良外,还存在与该诊断相符的改变。