Copper J A
Pulmonary Section, Birmingham Veterans Administration Medical Center, Alabama, USA.
Adv Intern Med. 1997;42:231-68.
Pulmonary reactions to drugs are a significant clinical problem and serve as a model for lung injury owing to other causes. Pulmonary reactions to certain drugs, such as bleomycin, carmustine, and amiodarone, greatly limit the use of these drugs. If research can distinguish the toxic from the therapeutic mechanisms of these and other drugs perhaps more effective therapies can be designed.
药物引起的肺部反应是一个重大的临床问题，并且可作为其他原因导致肺损伤的一个模型。某些药物，如博来霉素、卡莫司汀和胺碘酮，引起的肺部反应极大地限制了这些药物的使用。如果研究能够区分这些药物和其他药物的毒性机制与治疗机制，或许就能设计出更有效的治疗方法。
