Bausela B A, García-Ara M C, Martín Esteban M, Boyanó Martínez T B, Diaz Pena J M, Ojeda Casas J A
Allergology Service, La Paz Hospital, Madrid, Spain.
Ann Allergy Asthma Immunol. 1997 Feb;78(2):213-6. doi: 10.1016/s1081-1206(10)63389-3.
Hen's egg is frequently implicated in food allergy in children. Sometimes this allergy is associated with bird protein sensitization.
A study was conducted to establish the possible role of bird protein sensitization in the clinical picture and evolution of egg allergy in patients with both egg and bird sensitization.
Epidemiologic and clinical characteristics and the results of allergic study of 27 patients with both egg and bird allergy were compared with those of a control group of 19 egg-allergic patients without bird protein sensitization. All patients were evaluated clinically each year during the 4 years subsequent to the beginning of the study or until clinical tolerance to egg was achieved.
Patients with bird sensitization had more frequent digestive and respiratory symptoms related to egg ingestion compared with the control group. At the end of follow-up. 15% of the bird sensitized patients and 58% of the controls tolerated egg. Egg yolk sensitization was the major sensitization in bird-sensitized patients.
It is necessary to exclude sensitization to bird proteins in egg-allergic patients, mainly when they show respiratory or digestive symptoms after egg ingestion, the egg allergy persists over a long period of time or egg yolk sensitization is strong.
鸡蛋常引发儿童食物过敏。有时这种过敏与鸟类蛋白致敏有关。
开展一项研究，以确定鸟类蛋白致敏在同时对鸡蛋和鸟类致敏的患者鸡蛋过敏的临床表现及病程中可能发挥的作用。
将27例对鸡蛋和鸟类均过敏的患者的流行病学和临床特征以及过敏研究结果，与19例对鸡蛋过敏但无鸟类蛋白致敏的对照组患者进行比较。在研究开始后的4年里，每年对所有患者进行临床评估，直至达到对鸡蛋的临床耐受或研究结束。
与对照组相比，对鸟类致敏的患者摄入鸡蛋后出现消化和呼吸道症状的频率更高。随访结束时，15%的鸟类致敏患者和58%的对照组患者对鸡蛋产生耐受。蛋黄致敏是鸟类致敏患者的主要致敏类型。
有必要排除鸡蛋过敏患者对鸟类蛋白的致敏，尤其是当他们在摄入鸡蛋后出现呼吸道或消化症状、鸡蛋过敏长期持续或蛋黄致敏强烈时。
