Blume W T, Girvin J P, McLachlan R S, Gilmore B E
University Hospital, University of Western Ontario, London, Canada.
Epilepsia. 1997 Feb;38(2):164-7. doi: 10.1111/j.1528-1157.1997.tb01092.x.
Temporal lobectomy abolished complex partial seizures (CPSs) in 14 consecutive children (12 years or younger) whose presurgical evaluation included clinical analysis, scalp EEG, and neuroimaging. Seizures of 13 of 14 patients began with a simple partial component whose symptoms were suggestive of limbic system involvement. EEG recorded clinically typical seizures arising from the ultimately operated on temporal lobe in seven (50%) and never falsely lateralized seizure origin. Most active interictal spikes arose from the epileptogenic temporal lobe in 13 (93%) and never falsely lateralized epileptogenesis. Neuroimaging disclosed epileptogenic lesions in all: magnetic resonance imaging (MRI; 11 patients) and computed tomography (CT; three patients). Children may obtain relief from CPSs by temporal lobectomy without invasive electroencephalography.
颞叶切除术使14名连续的儿童（12岁及以下）的复杂部分性发作（CPS）得到缓解，这些儿童术前评估包括临床分析、头皮脑电图和神经影像学检查。14名患者中有13名的发作始于简单部分性发作成分，其症状提示边缘系统受累。脑电图记录到临床上典型的发作起源于最终接受手术的颞叶，7例（50%）如此，且从未错误地定位发作起源。大多数发作间期活跃棘波起源于致痫性颞叶，13例（93%）如此，且从未错误地定位癫痫发生。神经影像学检查在所有患者中均发现致痫性病变：磁共振成像（MRI；11例患者）和计算机断层扫描（CT；3例患者）。儿童可通过颞叶切除术缓解复杂部分性发作，而无需进行侵入性脑电图检查。
