Jetten M S, Logemann S, Muyzer G, Robertson L A, de Vries S, van Loosdrecht M C, Kuenen J G
Kluyver Laboratory for Biotechnology, Delft University of Technology, The Netherlands.
Antonie Van Leeuwenhoek. 1997 Feb;71(1-2):75-93. doi: 10.1023/a:1000150219937.
Some aspects of inorganic nitrogen conversion by microorganisms like N2O emission and hydroxylamine metabolism studied by Beijerinck and Kluyver, founders of the Delft School of Microbiology, are still actual today. In the Kluyver Laboratory for Biotechnology, microbial conversion of nitrogen compounds is still a central research theme. In recent years a range of new microbial processes and process technological applications have been studied. This paper gives a review of these developments including, aerobic denitrification, anaerobic ammonium oxidation, heterotrophic nitrification, and formation of intermediates (NO2-, NO, N2O), as well as the way these processes are controlled at the genetic and enzyme level.
由代尔夫特微生物学派的创始人拜耶林克和克吕弗所研究的微生物无机氮转化的某些方面，如一氧化二氮排放和羟胺代谢，至今仍然具有现实意义。在克吕弗生物技术实验室，氮化合物的微生物转化仍然是一个核心研究主题。近年来，人们对一系列新的微生物过程和工艺技术应用进行了研究。本文对这些进展进行了综述，包括好氧反硝化、厌氧氨氧化、异养硝化以及中间体（NO2-、NO、N2O）的形成，以及这些过程在基因和酶水平上的控制方式。
