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2型糖尿病与慢性肾功能不全:肾移植还是血液透析治疗?

Type II diabetes mellitus and chronic renal insufficiency: renal transplantation or haemodialysis treatment?

作者信息

Hirschl M M

机构信息

Department of Emergency Medicine, University of Vienna, Austria.

出版信息

Nephrol Dial Transplant. 1996;11 Suppl 9:98-9. doi: 10.1093/ndt/11.supp9.98.

DOI:10.1093/ndt/11.supp9.98
PMID:9050043
Abstract

The proportion of type II diabetic patients requiring renal replacement therapy has increased over the last 15 years. The ideal treatment for these patient is still a matter of dispute. Diabetic patients with a history of myocardial infarction, stroke or peripheral gangrene prior to renal replacement therapy had a worse prognosis compared with patients without vascular complications even after renal transplantation. The main causes of death were myocardial infarction and sepsis. A history of severe vascular complications prior to renal replacement therapy is an independent factor of decreased survival in type II diabetic patients. Renal transplantation significantly improved survival of diabetic patients without vascular complications and should be considered as the treatment of choice in this group of patients.

摘要

在过去15年中,需要肾脏替代治疗的II型糖尿病患者比例有所增加。对于这些患者的理想治疗方法仍存在争议。与没有血管并发症的患者相比,在进行肾脏替代治疗前有心肌梗死、中风或外周坏疽病史的糖尿病患者,即使在肾移植后预后也较差。主要死亡原因是心肌梗死和败血症。在进行肾脏替代治疗前有严重血管并发症的病史是II型糖尿病患者生存率降低的独立因素。肾移植显著提高了无血管并发症糖尿病患者的生存率,应被视为这类患者的首选治疗方法。

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引用本文的文献

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Clin Exp Nephrol. 2005 Jun;9(2):164-9. doi: 10.1007/s10157-005-0346-y.
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Kidney transplantation in patients with type 1 diabetes mellitus: long-term prognosis for patients and grafts.1型糖尿病患者的肾移植:患者及移植物的长期预后
Korean J Intern Med. 2001 Jun;16(2):98-104. doi: 10.3904/kjim.2001.16.2.98.