一名非免疫功能低下患者因B19细小病毒感染导致危及生命的贫血。

Life-threatening anaemia caused by B19 parvovirus infection in a non-immunocompromised patient.

作者信息

Biesma D H, Nieuwenhuis H K

机构信息

Department of Haematology, University Hospital Utrecht, Netherlands.

出版信息

Neth J Med. 1997 Feb;50(2):81-4. doi: 10.1016/s0300-2977(96)00076-9.

DOI:10.1016/s0300-2977(96)00076-9

PMID:9050335

Abstract

A 21-year-old Surinam boy suffering from a combined heterozygous sickle-cell beta-thalassaemia presented with an extreme anaemia (haemoglobin concentration 0.7 mmol/l) and severe haemolysis without signs of increased erythropoiesis. An acute B19 parvovirus infection was diagnosed by a transient increase of IgM anti-B19 parvovirus titres and a positive polymerase chain reaction for B19 parvovirus. The patient recovered spontaneously after a short period of supportive care with red cell transfusions and mechanical ventilation.

摘要

一名患有镰状细胞β地中海贫血复合杂合子的21岁苏里南男孩出现了严重贫血（血红蛋白浓度0.7 mmol/L）和严重溶血，且无红细胞生成增加的迹象。通过IgM抗B19细小病毒滴度的短暂升高和B19细小病毒聚合酶链反应阳性诊断为急性B19细小病毒感染。在经过一段时间的红细胞输注和机械通气支持治疗后，患者自行康复。