一种适用于冠状动脉内使用的前视血管内超声导管。
A forward-viewing intravascular ultrasound catheter suitable for intracoronary use.
作者信息
Liang D H, Hu B S
机构信息
Division of Cardiovascular Medicine, Stanford University Hospital, CA 94305, USA.
出版信息
Biomed Instrum Technol. 1997 Jan-Feb;31(1):45-53.
Current intravascular ultrasound (IVUS) catheters provide a transverse cross-sectional view of the blood vessel, thus limiting their ability to visualize severely stenosed or occluded vessels. Forward-viewing IVUS devices can overcome these limitations. Previously described forward-viewing IVUS catheters are mechanically complex, making them too bulky for use in coronary arteries. A new design for small-forward viewing IVUS catheters was developed. Using this design, flexible 5-Fr (1.6 mm diameter) and 8-Fr (2.6 mm diameter) prototype catheters up to 110 cm long, suitable for intravascular work, were constructed. Imaging of cadaver arterial segments was performed using these prototype catheters. Structures such as branches and plaque and features such as calcium were well seen with these catheters. Correlation of lumen dimensions measured with the IVUS catheters and by histology (HIST) was excellent: IVUS = 1.06 x HIST - 1.45 mm, r2 = 0.98. This new technology holds promise as a tool for guiding intravascular interventions.
当前的血管内超声（IVUS）导管提供血管的横向横截面视图，因此限制了它们可视化严重狭窄或闭塞血管的能力。前视IVUS设备可以克服这些限制。先前描述的前视IVUS导管机械结构复杂，使其体积过大而无法用于冠状动脉。一种用于小型前视IVUS导管的新设计被开发出来。采用这种设计，构建了长度达110厘米、适用于血管内操作的5F（直径1.6毫米）和8F（直径2.6毫米）柔性原型导管。使用这些原型导管对尸体动脉段进行成像。这些导管能够清晰地看到分支、斑块等结构以及钙化等特征。IVUS导管测量的管腔尺寸与组织学（HIST）测量结果的相关性极佳：IVUS = 1.06×HIST - 1.45毫米，r2 = 0.98。这项新技术有望成为指导血管内介入治疗的工具。
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