[Role of alterations of carbohydrate metabolism in the mechanism of decreasing the contractile function of the myocardium in patients with diabetes mellitus].

Changes in the myocardial contractile function were studied in 44 patients with diabetes mellitus by phasic analysis of the systole of the left ventricle, depending on the level and marked variations in glycemia in the course of 24 hours. The most pronounced phasic shifts by the 1 type of hypodynamia, pointing to reduction of the myocardial contractile function, were revealed in prolonged hyperglycemia, hypoglycemia, and a sharp fall of the blood sugar level at the period of marked 24-hour variations in glycemia. The results of investigations substantiated the fact that stable compensation of diabetes served as the active prophylactic measure of cardiovascular affections in this disease.