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[碳水化合物代谢改变在糖尿病患者心肌收缩功能降低机制中的作用]

[Role of alterations of carbohydrate metabolism in the mechanism of decreasing the contractile function of the myocardium in patients with diabetes mellitus].

作者信息

Litvinenko A F, Donish R M

出版信息

Probl Endokrinol (Mosk). 1977 Jul-Aug;23(4):14-9.

PMID:905254
Abstract

Changes in the myocardial contractile function were studied in 44 patients with diabetes mellitus by phasic analysis of the systole of the left ventricle, depending on the level and marked variations in glycemia in the course of 24 hours. The most pronounced phasic shifts by the 1 type of hypodynamia, pointing to reduction of the myocardial contractile function, were revealed in prolonged hyperglycemia, hypoglycemia, and a sharp fall of the blood sugar level at the period of marked 24-hour variations in glycemia. The results of investigations substantiated the fact that stable compensation of diabetes served as the active prophylactic measure of cardiovascular affections in this disease.

摘要

通过对44例糖尿病患者左心室收缩期进行阶段性分析,研究心肌收缩功能的变化,该分析取决于24小时内血糖水平及显著波动情况。在长期高血糖、低血糖以及血糖水平在24小时显著波动期间急剧下降时,发现最明显的阶段性变化为1型动力不足,这表明心肌收缩功能降低。研究结果证实了一个事实,即糖尿病的稳定代偿是预防该疾病心血管病变的积极措施。

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