Holzegel K
Phlebologie. 1977 Apr-Jun;30(2):169-72.
The events during a sclerosant injection were controlled radiographically. Vistarine forte containing 21.5% of total iodine makes the distribution of fluid clearly visible, both opacifying and sclerosing. 1 ml of air precedes the injection of 0.5 ml of sclerosant. This has shown that the "air-block", as found in the syringe, is not exactly a cushion of air separating the vessel wall from contact with the circulating blood. The air is distributed like a collar of pearls along the vein walls. These bubbles of air remain visible for a long time in the varicose convultions and this tend to hinder contact between the sclerosant and the intima of the varicose vein. As the slides show, it is a well demarcated segment of the varicose vein which comes into effective contact with the sclerosant. It is precisely this segment which subsequently becomes sclerosed. The sclerosant seeks a centripetal pathway in all positions, lying standing and sitting. The therapeutic effect is the same, and is independent of the position of the patient at the time of the injection of sclerosant.
硬化剂注射过程通过影像学进行控制。含21.5%总碘量的强力泛影葡胺使液体分布清晰可见，兼具造影和硬化作用。在注射0.5毫升硬化剂之前先注入1毫升空气。这表明注射器中发现的“气栓”并非精确地是将血管壁与循环血液隔开的空气垫。空气像一串珍珠一样沿着静脉壁分布。这些气泡在静脉曲张中长时间可见，这往往会阻碍硬化剂与曲张静脉内膜的接触。如幻灯片所示，与硬化剂有效接触的是曲张静脉中界限分明的一段。正是这一段随后发生硬化。无论患者处于卧位、站立位还是坐位，硬化剂均沿向心路径分布。治疗效果相同，且与注射硬化剂时患者的体位无关。
