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[阿司匹林和安乃近对白细胞自然游走抑制的体内试验在哮喘三联征特异性诊断中的应用]

[The in-vivo test of the inhibition of leukocyte natural migration with aspirin and analgin in the specific diagnosis of the asthmatic triad].

作者信息

Kanchurina N A, Poroshina Iu A, Prasolova N I, Zemskov V M

出版信息

Ter Arkh. 1996;68(12):25-8.

PMID:9054032
Abstract

Asthmatic triad (AT) is a clinical syndrome incorporating bronchial asthma (BA), recurrent nasal and sinus polyps, intolerance of aspirin, derivatives of pirasolone and other nonsteroid antiinflammatory drugs. Specific diagnosis of aspirin and analgin intolerance in patients with AT was made using the test of natural leukocyte emigration inhibition in vivo in the oral cavity. The test was performed in 22 patients with AT and 13 patients with BA with pollenosis without aspirin and analgin intolerance. In all the patients the test provided positive results, in control patients these were negative. High significance, safety and simplicity of the test made it applicable for specific diagnosis of AT in allergological and pulmonological departments.

摘要

哮喘三联征(AT)是一种临床综合征,包括支气管哮喘(BA)、复发性鼻息肉和鼻窦息肉、对阿司匹林、匹拉索酮衍生物及其他非甾体抗炎药不耐受。采用口腔内自然白细胞游走抑制体内试验对AT患者的阿司匹林和安乃近不耐受进行特异性诊断。对22例AT患者和13例伴有花粉症但无阿司匹林和安乃近不耐受的BA患者进行了该试验。所有患者的试验结果均为阳性,对照患者的结果为阴性。该试验具有高度的显著性、安全性和简便性,适用于变态反应科和肺病科对AT的特异性诊断。

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