Michel O, Naeije N, Bracamonte M, Sergysels R, Duchateau J
Rev Pneumol Clin. 1984;40(6):369-71.
Oral provocation tests using aspirin (n = 55), tartrazine (n = 37) and benzoate (n = 28) were performed in 55 asthmatic patients. A positive aspirin provocation test was observed in 15 patients (27%). These patients often had a past history of aspirin intolerance, 53% of them also had nasal polyposis and 5 out of 12 had associated tartrazine intolerance, while 2 out of 8 had associated benzoate intolerance. The authors consider that these features may help the clinician to detect the asthmatic patient at high risk of aspirin intolerance in whom a provocation test should be performed.
对55例哮喘患者进行了口服阿司匹林（n = 55）、酒石黄（n = 37）和苯甲酸盐（n = 28）激发试验。15例患者（27%）阿司匹林激发试验呈阳性。这些患者常有阿司匹林不耐受病史，其中53%还患有鼻息肉，12例中有5例伴有酒石黄不耐受，8例中有2例伴有苯甲酸盐不耐受。作者认为这些特征可能有助于临床医生识别有阿司匹林不耐受高风险的哮喘患者，对此类患者应进行激发试验。
