Barbarash O L, Martsiiash A A, Sheĭbak T V, Chukaeva I I, Korochkin I M, Syrnev V V
Ter Arkh. 1996;68(12):50-3.
Dependence of the response to helium-neon laser therapy (LT) on initial level and changes of blood plasma hydrocortisone (HC), testosterone (T), diene conjugates (DC) concentration, general antioxidant activity (AOA) of blood plasma, TxB and 6-keto-PGF were estimated in 147 patients with ischemic heart disease and stable angina. The response to LT was observed in patients with high levels of HC, T, AOA and 6-keto-PGF1 alpha. A significant increase of DC was noted in these patients too. The minimal level of HC. T and AOA was recorded in patients with negative clinical effect. The treatment only aggravated HC, T and AOA deficiency and raised DC and TxB level. The findings suggest that the effect of LT is based on modulation of nonspecific adaptive mechanisms.
对147例缺血性心脏病和稳定型心绞痛患者，评估了氦氖激光疗法（LT）的疗效与血浆氢化可的松（HC）、睾酮（T）、二烯共轭物（DC）浓度的初始水平及变化、血浆总抗氧化活性（AOA）、血栓素B（TxB）和6-酮-前列环素（6-keto-PGF）之间的关系。在HC、T、AOA和6-酮-前列环素1α水平较高的患者中观察到了对LT的反应。这些患者的DC也显著增加。临床效果为阴性的患者中记录到HC、T和AOA的最低水平。治疗仅加重了HC、T和AOA的缺乏，并提高了DC和TxB水平。研究结果表明，LT的作用基于非特异性适应性机制的调节。
