Vasil'ev A P, Strel'tsova N N, Zhikhareva A I, Kiianiuk N S, Zimina T P
Ter Arkh. 1996;68(12):47-50.
Laser therapy of coronary patients significantly diminished total cholesterol, low and very low density lipoproteins, triglycerides and atherogenic index persisting for 3-6 months. Primary changes in the structure of the lipid bilayer of a red cell membrane in response to laser radiation are considered to be an effect of the physical factor characterized by activation of lipid peroxidation, phospholipolysis, by growth of membrane cholesterol content (phase I). Mobilization of the adaptive mechanisms was accompanied by positive shifts in the structure pattern of a biomembrane with return to initial condition by the end of the therapy course (phase II). Further (III) phase of subcellular changes resultant from quantum effects lasted for 3 months and brought activation of the antioxidant system, reorganization of phospholipid membrane composition, an increase in osmotic resistance of red cells. This may produce a positive tendency in IHD.
对冠心病患者进行激光治疗可显著降低总胆固醇、低密度脂蛋白和极低密度脂蛋白、甘油三酯以及致动脉粥样化指数，且这种效果可持续3至6个月。红细胞膜脂质双层结构对激光辐射的初始变化被认为是一种物理因素的作用，其特征为脂质过氧化、磷脂分解的激活以及膜胆固醇含量的增加（第一阶段）。适应性机制的动员伴随着生物膜结构模式的正向变化，在治疗过程结束时恢复到初始状态（第二阶段）。由量子效应导致的亚细胞变化的进一步（第三）阶段持续3个月，带来抗氧化系统的激活、磷脂膜成分的重组以及红细胞渗透抗性的增加。这可能会在缺血性心脏病中产生积极趋势。
