[不同类型红斑狼疮患者淋巴细胞组蛋白分析]
[An analysis of the lymphoid cell histones in patients with different forms of lupus erythematosus].
作者信息
Khamaganova I V, Savina M I, Khromova S S, Reshina V M, Aleĭnikova N V
出版信息
Ter Arkh. 1996;68(12):82-4.
PMID:9054053
Abstract
The study was made of lisine- and arginine-rich histone fractions and DNA in lymphocytes of peripheral blood in patients with lupus erythematosus. The findings showed intranuclear changes of immunocompetent cells in various forms of the disease. The above parameters may be used in the diagnosis, evaluation of treatment efficacy, prognosis.
摘要
对红斑狼疮患者外周血淋巴细胞中富含赖氨酸和精氨酸的组蛋白组分及DNA进行了研究。研究结果显示了该疾病不同形式下免疫活性细胞的核内变化。上述参数可用于诊断、评估治疗效果及预后。
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