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[红斑狼疮:不同治疗方法对淋巴细胞核内特征的影响]

[Lupus erythematosus: effects of different therapeutic methods on intranuclear characteristics of lymphoid cells].

作者信息

Khamaganova I V, Savina M I, Khromova S S, Reshina V M, Aleĭnikova N V

出版信息

Ter Arkh. 1997;69(12):76-8.

PMID:9503543
Abstract

In lymphocytes of peripheral blood from 46 patients with various forms of lupus erythematosus measurements were made of histone fractions and DNA. It is proved that intranuclear characteristics of lymphoid cells can be used in the choice of treatment and assessment of its efficacy. Lupus erythematosus treatment with glucocorticoids (diprospan, diprospan + celeston) is effective in correction of intranuclear lymphocyte changes in this disease.

摘要

对46例各种类型红斑狼疮患者外周血淋巴细胞的组蛋白组分和DNA进行了测定。结果证明,淋巴细胞的核内特征可用于治疗方案的选择及其疗效评估。用糖皮质激素(得宝松、得宝松+赛利松)治疗红斑狼疮对纠正该病淋巴细胞的核内变化有效。

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