Liebisch B, Schwarz S
Institut für Kleintierforschung Celle/Merbitz, Bundesforschungsanstalt für Landwirtschaft Braunschweig-Völkenrode (FAL).
Berl Munch Tierarztl Wochenschr. 1996 Sep;109(9):348-54.
Various molecular typing methods for the analysis of zoonotic bacterial pathogens have been developed during the last decade. Because of their high discriminatory power, these methods have been increasingly used even in routine diagnostics. The description of several independent genotypic characteristics in addition to that of the phenotypic properties enables a complex and exact identification of bacterial strains. Molecular techniques such as plasmid analysis, ribotyping. IS200 typing as well as macrorestriction analysis represent components of a basic molecular typing system for Salmonella isolates which proved to be suitable for various epidemiological applications.
在过去十年中,已开发出多种用于分析人畜共患细菌病原体的分子分型方法。由于其具有较高的鉴别力,这些方法甚至在常规诊断中也越来越多地被使用。除了表型特性的描述外,对几种独立基因型特征的描述能够对细菌菌株进行复杂而准确的鉴定。诸如质粒分析、核糖体分型、IS200分型以及宏观限制性分析等分子技术是沙门氏菌分离株基本分子分型系统的组成部分,事实证明该系统适用于各种流行病学应用。