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纤维蛋白胶在小梁切除术后复杂性低眼压治疗中的应用

Fibrin sealant in the management of complicated hypotony after trabeculectomy.

作者信息

Grewing R, Mester U

机构信息

Department of Ophthalmology, Bundesknapppschaft's Hospital, Sulzbach/Saar, Germany.

出版信息

Ophthalmic Surg Lasers. 1997 Feb;28(2):124-7.

PMID:9054483
Abstract

BACKGROUND AND OBJECTIVE

In the postoperative course of trabeculectomy, hypotony may cause choroidal detachment with shallowing of the anterior chamber. If conservative medical treatment fails, a surgical revision may become necessary. To achieve only a temporary seal of the scleral flap, a subconjunctival tamponade with fibrin glue was performed.

PATIENTS AND METHODS

Two patients with corneal decompensation as a result of cornea-lens contact complicating hypotony with massive choroidal detachment are described. Hypotony occurred after trabeculectomy in one case and after combined cataract and glaucoma surgery in another case, and was not correlated to a leaking bleb. Temporary tamponade of the scleral flap was achieved by subconjunctival injection of fibrin sealant.

RESULTS

After the fibrin sealant was applied, the choroidal detachment resolved and intraocular pressure increased to normal. During the follow-up period of 6 months, a functioning bleb developed.

CONCLUSION

Subconjunctival application of fibrin sealant is effective for temporary closure of the scleral flap after trabeculectomy in eyes with massive hypotony syndrome.

摘要

背景与目的

在小梁切除术后的病程中,低眼压可能导致脉络膜脱离并伴有前房变浅。如果保守药物治疗失败,可能需要进行手术修复。为了仅实现巩膜瓣的临时封闭,采用了纤维蛋白胶结膜下填塞术。

患者与方法

描述了2例因角膜 - 晶状体接触导致角膜失代偿并伴有大量脉络膜脱离的低眼压患者。1例低眼压发生在小梁切除术后,另1例发生在白内障与青光眼联合手术后,且与滤过泡渗漏无关。通过结膜下注射纤维蛋白封闭剂实现巩膜瓣的临时填塞。

结果

应用纤维蛋白封闭剂后,脉络膜脱离消退,眼压恢复正常。在6个月的随访期内,形成了功能性滤过泡。

结论

对于伴有大量低眼压综合征的眼,小梁切除术后结膜下应用纤维蛋白封闭剂可有效临时封闭巩膜瓣。

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