Tang W, Weil M H, Schock R B, Sato Y, Lucas J, Sun S, Bisera J
Institute of Critical Care Medicine, Palm Springs, Calif 92262-5309, USA.
Circulation. 1997 Mar 4;95(5):1335-40. doi: 10.1161/01.cir.95.5.1335.
We describe a new manual method of phased chest and abdominal compression-decompression with a Lifestick resuscitator for cardiopulmonary resuscitation (CPR).
Ventricular fibrillation (VF) was induced in 20 domestic pigs. After either 5 or 7 minutes of untreated VF, either phased chest and abdominal compression-decompression (Lifestick resuscitator) or precordial compression was initiated. Defibrillation was attempted at 2 minutes after the start of CPR. For the animals in which VF was untreated for 7 minutes, epinephrine was administered in doses of 20 micrograms/kg at 2 minutes after start of CPR. The coronary perfusion pressure generated by the Lifestick resuscitator was more than twofold greater (P < .01) than that generated by conventional precordial compression. Of 5 control animals, none were resuscitated after 5 minutes of VF. However, each of 5 animals treated with the Lifestick resuscitator was resuscitated (P < .01) and survived after 48 hours (P < .01). When untreated VF was prolonged to 7 minutes and epinephrine was administered, only 2 of the 5 control animals were resuscitated, and none of them survived for more than 4 hours. However, each of the Lifestick-treated animals was resuscitated and survived for more than 48 hours (P < .01).
Phased chest and abdominal compression-decompression substantially increased hemodynamic efficacy of CPR and outcome in terms of successful resuscitation, 48-hour survival, and cerebral recovery.
我们描述了一种使用救生棒复苏器进行分阶段胸腹部按压-减压的新型手动心肺复苏(CPR)方法。
在20头家猪中诱发室颤(VF)。在未经治疗的室颤持续5或7分钟后,开始进行分阶段胸腹部按压-减压(使用救生棒复苏器)或心前区按压。在CPR开始2分钟后尝试除颤。对于室颤未经治疗达7分钟的动物,在CPR开始2分钟时给予剂量为20微克/千克的肾上腺素。救生棒复苏器产生的冠状动脉灌注压比传统心前区按压产生的冠状动脉灌注压高出两倍多(P <.01)。5只对照动物在室颤5分钟后均未复苏。然而,使用救生棒复苏器治疗的5只动物均成功复苏(P <.01)并在48小时后存活(P <.01)。当未经治疗的室颤延长至7分钟并给予肾上腺素时,5只对照动物中只有2只复苏,且均未存活超过4小时。然而,使用救生棒治疗的每只动物均复苏并存活超过48小时(P <.01)。
分阶段胸腹部按压-减压在成功复苏、48小时存活和脑恢复方面显著提高了CPR的血流动力学效果和预后。