Kurtz D, Trapp C, Kieny M T, Wassmer J M, Mugnaioni M D, Pack A, Hoff E
Rev Electroencephalogr Neurophysiol Clin. 1977 Jan-Mar;7(1):62-9. doi: 10.1016/s0370-4475(77)80036-1.
The authors compare recovery and the post-anaesthetic period in 45 patients anaesthetised with a combination of either pentothal, nitrous oxide, fluothane and dolosal (group 1, 24 subjects), or of pentothal, nitrous oxide and phenoperidine (group 2, 21 subjects). The quality of recovery was judged at the end of anaesthesia by determining of occurrence of the first response to 3 types of stimulation (calling the name, noise and pain) and the density of these responses during each minute. During the post-anaesthetic period the respective percentages of wakefulness and sleep were calculated. In this way the authors demonstrate a significant (P less than 0.01) shortening in recovery time for group 2, reactivity to own name occurring first in both groups, and a very significant (P less than 0.001) increase in the percentage of physiological sleep in subjects of group 2 during the post-anaesthetic stage.
作者比较了45例分别采用硫喷妥钠、氧化亚氮、氟烷和多沙普仑联合麻醉（第1组，24例）或硫喷妥钠、氧化亚氮和苯哌啶麻醉（第2组，21例）患者的苏醒情况及麻醉后阶段。通过确定对三种刺激（呼唤姓名、噪音和疼痛）的首次反应出现情况以及每分钟这些反应的密度来判断麻醉结束时的苏醒质量。在麻醉后阶段，计算清醒和睡眠的各自百分比。通过这种方式，作者证明第2组的苏醒时间显著缩短（P<0.01），两组中对自己姓名的反应均最先出现，并且第2组患者在麻醉后阶段的生理性睡眠百分比非常显著增加（P<0.001）。
