Snyder P J, Harris L J
Department of Neurology, Medical College of Pennsylvania.
Brain Cogn. 1997 Feb;33(1):18-32. doi: 10.1006/brcg.1997.0882.
The intracarotid sodium amobarbital procedure (IAP) is currently regarded as the best method of the determination of hemispheric specialization for speech, and it is universally relied on as a prognostic test for patients with medically refractory epilepsy who are candidates for neurosurgical intervention. Since its initial development, the IAP also has been adapted for assessing lateralized mesiotemporal contributions to memory functioning in this patient population, and it is now in wide use for both basic and applied research in behavioral neuroscience on language, memory, visuospatial functions, emotion, attention, and consciousness. Despite the IAP's wide range of applications, little has been said about its history and development. This essay recounts and discusses this history.
颈动脉内注射异戊巴比妥试验（IAP）目前被认为是确定言语半球特化的最佳方法，并且它被普遍用作对药物难治性癫痫且适合神经外科干预的患者进行预后测试。自最初开发以来，IAP也已被用于评估该患者群体中内侧颞叶对记忆功能的偏侧化贡献，并且它现在广泛应用于行为神经科学中关于语言、记忆、视觉空间功能、情感、注意力和意识的基础研究和应用研究。尽管IAP应用广泛，但关于其历史和发展却鲜有提及。本文叙述并讨论了这段历史。
