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中风、残疾与痴呆:一项人口调查结果

Stroke, disability, and dementia: results of a population survey.

作者信息

Prencipe M, Ferretti C, Casini A R, Santini M, Giubilei F, Culasso F

机构信息

Department of Neurological Sciences, Universita degli Studi La Sapienza, Rome, Italy.

出版信息

Stroke. 1997 Mar;28(3):531-6. doi: 10.1161/01.str.28.3.531.

DOI:10.1161/01.str.28.3.531
PMID:9056607
Abstract

BACKGROUND AND PURPOSE

Stroke, disability, and dementia often coexist in elderly people. We assessed the prevalence and mutual association of these disorders in an elderly rural population.

METHODS

We carried out a door-to-door survey on all subjects aged 65 years or over (n=1032) living in a rural community. To evaluate the associations between stroke and disability and between stroke and dementia, we compared stroke patients with all stroke-free subjects by means of two multiple logistic regression analyses. Subsequently, we performed a case-control analysis by comparing each stroke patient with two age- and sex-matched population control subjects.

RESULTS

We identified 80 stroke patients. After the exclusion of five incident cases, the prevalence of stroke was 7.3% (95% confidence interval [CI], 5.7 to 8.9). Sixty-five percent of stroke survivors and 23% of stroke-free subjects were disabled (age- and sex-adjusted odds ratio [OR], 6.3; 95% CI, 3.7 to 10.9). Thirty percent of stroke survivors and 5.7% of stroke-free subjects were demented. The OR for dementia (stroke patients versus all stroke-free subjects) was 5.8 (95% CI, 3.1 to 10.8) and became 3.4 (95% CI, 1.5 to 8.0) in the case-control analysis.

CONCLUSIONS

In our population, the prevalence of stroke was higher than in previous studies. Stroke survivors were more disabled and more at risk for dementia than stroke-free subjects.

摘要

背景与目的

中风、残疾和痴呆症在老年人中常常并存。我们评估了这些疾病在农村老年人群中的患病率及其相互关联。

方法

我们对居住在一个农村社区的所有65岁及以上的受试者(n = 1032)进行了挨家挨户的调查。为了评估中风与残疾之间以及中风与痴呆症之间的关联,我们通过两次多元逻辑回归分析,将中风患者与所有未患中风的受试者进行了比较。随后,我们通过将每位中风患者与两名年龄和性别匹配的人群对照受试者进行比较,进行了病例对照分析。

结果

我们识别出80名中风患者。排除5例新发病例后,中风的患病率为7.3%(95%置信区间[CI],5.7至8.9)。65%的中风幸存者和23%的未患中风的受试者存在残疾(年龄和性别调整后的优势比[OR],6.3;95%CI,3.7至10.9)。30%的中风幸存者和5.7%的未患中风的受试者患有痴呆症。痴呆症的OR(中风患者与所有未患中风的受试者相比)为5.8(95%CI,3.1至10.8),在病例对照分析中变为3.4(95%CI,1.5至8.0)。

结论

在我们的研究人群中,中风的患病率高于先前的研究。与未患中风的受试者相比,中风幸存者残疾程度更高,患痴呆症的风险也更高。

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