Ogaard B, Arends J, Helseth H, Dijkman G, van der Kuijl M
Department of Orthodontics, Faculty of Dentistry, University of Oslo, Norway.
Am J Orthod Dentofacial Orthop. 1997 Feb;111(2):199-202. doi: 10.1016/s0889-5406(97)70216-6.
The fluoride level in saliva is considered an important parameter in caries prevention. Elevation of the salivary fluoride level by a fluoride-releasing orthodontic bonding adhesive would most likely be beneficial in the prevention of enamel caries. In this study, the fluoride level in saliva was measured after bonding brackets with a visible light-curing adhesive containing fluoride (12.4 wt% total F). The fluoride released from the adhesive has been shown in a previous study to inhibit demineralization adjacent to orthodontic brackets in vivo. Twenty-four patients each had 20 brackets bonded and saliva samples taken before bonding (t = 0) and after 1, 3, and 6 months. The participants were requested to brush daily with a fluoride toothpaste during the study period. The saliva fluoride analysis was done with the microdiffusion method. The analysis of the saliva showed fluoride levels (+/- SD) of 0.011 +/- 0.007, 0.011 +/- 0.009, 0.0011 +/- 0.007, and 0.012 +/- 0.008 ppm at t = 0, 1, 3, and 6 months, respectively. There was no significant difference at the 5% level. The study indicated indirectly that the caries inhibiting effect of the orthodontic adhesive shown previously was most likely due to a localized fluoridation of the cariogenic environment rather than to an elevation of the fluoride level in saliva.
唾液中的氟含量被认为是预防龋齿的一个重要参数。含氟正畸粘结剂提高唾液氟含量很可能对预防牙釉质龋有益。在本研究中，用含氟（总氟含量12.4 wt%）的可见光固化粘结剂粘结托槽后，测量唾液中的氟含量。先前的一项研究已表明，该粘结剂释放的氟在体内可抑制正畸托槽附近的脱矿。24名患者每人粘结20个托槽，并在粘结前（t = 0）以及粘结后1、3和6个月采集唾液样本。在研究期间，要求参与者每天使用含氟牙膏刷牙。唾液氟分析采用微扩散法。唾液分析显示，在t = 0、1、3和6个月时，氟含量（±标准差）分别为0.011±0.007、0.011±0.009、0.011±0.007和0.012±0.008 ppm。在5%的水平上没有显著差异。该研究间接表明，先前显示的正畸粘结剂的防龋作用很可能是由于致龋环境的局部氟化，而非唾液中氟含量的升高。
