Ogaard B, Rezk-Lega F, Ruben J, Arends J
Department of Orthodontics, Dental Faculty, University of Oslo, Norway.
Am J Orthod Dentofacial Orthop. 1992 Apr;101(4):303-7. doi: 10.1016/S0889-5406(05)80322-1.
This study was designed to investigate the cariostatic potential in vivo of a visible light-curing adhesive for the bonding of orthodontic brackets. The fluoride release of the adhesive in water and saliva was also measured. Ten orthodontic patients with premolars to be extracted participated. One bracket with Heliosit-Orthodontic (no fluoride) was positioned on the buccal surface of one premolar (control), and another bracket with Orthodontic cement VP 862 (containing fluoride) was positioned on the experimental contralateral premolar. The adhesives were cured with a Heliolux II lamp, and the teeth were extracted after 4 weeks. The patients used a fluoride toothpaste during the experiment. The mineral content of the enamel adjacent to the brackets was determined by quantitative microradiography. The fluoride release from disk-shaped plates of the fluoride adhesive was measured in water for a 6-month period and in human saliva for 24 hours. The fluoride adhesive reduced lesion depths by about 48% than the nonfluoride adhesive (P less than 0.05, t test). The largest release of fluoride from the plates in water was observable within the first week. However, a significant amount of fluoride was still released after 6 months. The fluoride release in saliva was significantly lower in human saliva at pH 7 than in water (P less than 0.01, t test). When salivary pH was lowered to 4, to mimic a cariogenic challenge, the amount of fluoride released increased up to the value measured in water. It was concluded that the regular use of fluoride toothpastes is insufficient to inhibit lesion development around orthodontic brackets.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究旨在调查一种用于正畸托槽粘结的可见光固化胶粘剂在体内的防龋潜力。同时还测量了该胶粘剂在水和唾液中的氟释放量。十名需要拔除前磨牙的正畸患者参与了研究。在一侧前磨牙的颊面放置一个使用Heliosit-Orthodontic(不含氟)的托槽(对照组),在对侧实验性前磨牙上放置另一个使用正畸粘结剂VP 862(含氟)的托槽。用Heliolux II灯固化胶粘剂,4周后拔除牙齿。实验期间患者使用含氟牙膏。通过定量显微放射照相法测定托槽附近釉质的矿物质含量。在水中测量含氟胶粘剂圆盘状板6个月的氟释放量,在人唾液中测量24小时内的氟释放量。与不含氟的胶粘剂相比,含氟胶粘剂使病变深度降低了约48%(P<0.05,t检验)。在水中,圆盘状板在第一周内氟释放量最大。然而,6个月后仍有大量氟释放。在pH值为7的人唾液中,氟在唾液中的释放量明显低于在水中的释放量(P<0.01,t检验)。当唾液pH值降至4以模拟致龋挑战时,氟释放量增加至在水中测得的值。研究得出结论,定期使用含氟牙膏不足以抑制正畸托槽周围的病变发展。(摘要截短于250字)