Sailer M, Cabral D, Petty R E, Malleson P N
Department of Pediatrics, University of British Columbia, Vancouver.
J Rheumatol. 1997 Mar;24(3):586-8.
We describe 2 children with oligoarticular onset juvenile rheumatoid arthritis (JRA) with early erosive disease. Both patients were rheumatoid factor (RF) positive, but neither had HLA-DR4. These findings suggest RF is associated with early erosive disease, independent of HLA-DR4. RF positive oligoarticular onset JRA should probably be recognized as a separate subgroup of JRA.
我们描述了2例少关节型幼年类风湿关节炎（JRA）患儿，他们患有早期侵蚀性疾病。两名患者类风湿因子（RF）均为阳性，但均无HLA-DR4。这些发现表明RF与早期侵蚀性疾病相关，独立于HLA-DR4。RF阳性的少关节型JRA可能应被视为JRA的一个单独亚组。
