The influence of latent hyperprolactinaemia on the levels of LH, FSH, E2 and T in the midfollicular phase of the cycle.

The metoclopramide test for latent hyperprolactinaemia was done on 174 randomly chosen infertile women in the midfollicular phase of the cycle. 54 women had latent hyperprolactinaemia which was defined as a PRL level of at least 150 ng/ml after metoclopramide. Just before the metoclopramide was given, blood was taken to measure the levels of luteinizing hormone (LH) and follicle stimulating hormone (FSH), 17-beta estradiol (E2) and total testosterone (T). Women with latent hyperprolactinaemia had significantly lower levels of LH (p < 0.01) and E2 (p < 0.001) and higher levels of T (p < 0.05) in the midfollicular phase when compared with women without this condition. FSH levels showed no statistically significant difference.