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Gel electrophoretic mobility of charged particles in a medium with curved channels.

作者信息

Fridrikh S, Gotlib Y, Belenkij B

机构信息

Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia.

出版信息

Electrophoresis. 1997 Jan;18(1):26-33. doi: 10.1002/elps.1150180107.

DOI:10.1002/elps.1150180107
PMID:9059817
Abstract

A model of electrophoretic mobility of small charged particles (for example short DNA fragments) in media with curved channels is proposed. The medium is represented by a dense material embedding the curved channels accessible to the charged particles. The steady flow method is used to obtain an analytical expression of the particles' electrophoretic mobility as a function of the channel's shape. The analogy between the statistical properties of the channels and polymer chains (free-jointed and with the persistent mobility mechanism) is used.

摘要

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