Patel A M, Spector M
Department of Orthopedic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Biomaterials. 1997 Mar;18(5):441-7. doi: 10.1016/s0142-9612(96)00152-4.
Problems with total joint replacement that have surfaced in recent years have made reconsideration of more conservative hip reconstructive procedures compelling. Moreover, procedures such as hemiarthroplasty might benefit from newly developed materials that could provide more favourable tribological performance when employed as a counterface for articulation with articular cartilage. The objective of this study was to evaluate the tribology of a new biomaterial, oxidized zirconium, with articular cartilage in a laboratory test apparatus. Oxidized zirconium components are produced by oxidizing the zirconium alloy to form a relatively thick (7 microns), adherent, abrasion-resistant ceramic surface. We found that the coefficient of friction of bovine articular cartilage rubbed against oxidized zirconium was lower than with cobalt-chromium alloy control surfaces, and that there was a trend toward less wear with oxidized zirconium. A defined layer of degraded tissue was found on the surface of the articular cartilage specimens, providing some indication of the mechanism of wear. Results of this study warrant further investigation of oxidized zirconium as the bearing surface for hemiarthroplasty.
近年来全关节置换出现的问题使得重新考虑采用更为保守的髋关节重建手术变得十分必要。此外，诸如半关节置换术等手术可能会受益于新开发的材料，这些材料在作为与关节软骨进行关节活动的配对面使用时，能够提供更有利的摩擦学性能。本研究的目的是在实验室测试装置中评估一种新型生物材料——氧化锆与关节软骨之间的摩擦学特性。氧化锆部件是通过氧化锆合金形成相对较厚（7微米）、附着性好且耐磨的陶瓷表面而制成的。我们发现，牛关节软骨与氧化锆摩擦时的摩擦系数低于与钴铬合金对照表面摩擦时的系数，并且氧化锆的磨损有减少的趋势。在关节软骨标本表面发现了一层明确的退化组织层，这为磨损机制提供了一些线索。本研究结果值得对氧化锆作为半关节置换术的承重表面进行进一步研究。
